It happened at 7:15 a.m. Thursday in the southbound lanes of the Northeast Extension at mile post 24.8 in Whitpain Township.
Police say 49-year-old William Kishbaugh of Wapwallopen, Pa. was at the wheel of a tractor trailer and failed to obey posted signs instructing all trucks to use the left lane only.
The right front bumper of the tractor trailer struck a concrete barrier on the right shoulder of the highway, and Kishbaugh lost control of the rig. He veered into the left lane, striking a Honda Civic driven by 22-year-old Kristen Maehrer of Allentown, Pa.
The impact forced Maehrer's vehicle into the center concrete median barrier. The car rolled onto its right side and became wedged between the barrier and the tractor trailer with the driver's side of the car facing up.
Maehrer was flown by medical helicopter to Lehigh Valley Hospital with non-life-threatening injuries. Kishbaugh was driven to Mercy Suburban Hospital with minor injuries.
Traffic in both directions was shut down for several hours. All lanes were back open by 10:30 a.m.
There was no immediate word what charges, if any, might be filed.