Police were called out to 21st Street and Medary Avenue around 8:30 p.m. for reports of shots fired.
Police say an 18-year-old was shot once in the right shoulder, a 16-year-old was shot in the chest, a 15-year-old and a 20-year-old were both shot in the leg.
All of them were rushed to Einstein Medical Center where they are listed in stable condition.