The shooting occurred just after 10:00 p.m. in the 2600 block of Wolf Street.
According to police, the victim went into the backyard and was talking to 3-4 other males when shots rang out.
He was struck in the head and officers rushed him to the Hospital of the University of Pennsylvania.
He was pronounced dead a short time later.
Police have not said if there are any suspects or a motive.
The victim's name has not been released.