The incident happened around 3:45 a.m. in the 8700 block of Sagamore Road.
The officer's wife heard the suspects breaking into their home and she alerted her husband.
He confronted two men, shooting one of them who was later pronounced dead at the scene.
The other suspect fled in the officer's 2001 Honda Odyssey.
The officer and his wife were not injured and police remain on the scene investigating.