Debra Miller has not been seen since Saturday, November 17.
Authorities say Miller left her Essington home to go to the grocery store and did not return.
On Sunday, Miller's family and friends joined police to search the area. Her brother says his sister has never disappeared before.
Police do not suspect any foul play.
Miller is 5'8" tall, 130 pounds, with black hair and brown eyes.
Anyone with information on her whereabouts is asked to contact Tinicum Township Police at 610-521-3830.