Michael Peterman, 25, of the 4300 block of Freeland Street, was last seen at his home at 5:00 p.m. on Thursday December 6.
He is described as a white male, 25 years old, 5'4" tall with a thin build, short blond hair, green eyes and fair complexion.
He was last seen wearing a gray George Mason College hooded sweatshirt and blue jeans.
Police say Peterman suffers from depression and often frequents the area of Main and Carson Streets.
Anyone who has seen Peterman or has information on his whereabouts is asked to call the Philadelphia Police Department's Northwest Detective Division at 215-686-3353.