Firefighters were called to the unit block of East Avenue at 4:36 a.m. Wednesday.
The victim is identified as 62-year-old Ron Steward.
Neighbors woke up to a commotion and found Steward's wife, Diane, and his stepson already out of the house, standing in the driveway calling for Ron.
Investigators say it appears he stayed inside, trying to fight the flames by himself.
Images from Chopper 6 HD over the scene showed a large, single-family home engulfed in thick smoke and flames shooting through the roof.
There was no immediate word as to how the fire started, though initial word from the scene was that it may have started in the basement.
An autopsy is being performed on the victim.
Neighbors were stunned by the sudden loss of life. They say Ron Steward was a retired truck driver, an amiable man who spent a lot of time doing odd jobs around the house.
Because this was a fatal fire, the Gloucester County prosecutor's office is involved in the investigation. But, at this point, there doesn't appear to be any foul play involved.
Investigators have not determined where or how the fire started.