Police Commissioner Danielle Outlaw said just last week that the department was anticipating violence amid the warmer weather.
Around 1:30 a.m. Sunday, officers responded to a home invasion in the city's Feltonville section.
Investigators said two men wearing masks forced their way into a home along Rorer Street and demanded money from a man inside.
The suspects shot the man once in the chest.
The victim was taken into emergency surgery.
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Around the same time of night, a 19 year old was shot five times in the city's Kensington section, police said.
Investigators said the gunfire rang out along East Clearfield Street, just feet away from a makeshift memorial, for a person killed last week.
The man was taken to the hospital where he received emergency surgery. There is no word on his condition at this time.
There have been no arrests made in either case.
Anyone with information is asked to contact the police.