The two car crash occurred around 3:00 a.m. at the intersection of 23rd and Lombard streets.
Authorities say one car struck the other.
The striking car careened off the road and struck the dry cleaning business.
The driver then got out and fled, leaving the vehicle behind.
The other driver was uninjured.
Firefighters called Licenses and Inspections to the scene to inspect the integrity of the building.