The 12th seeded Wildcats (22-12) boarded a bus on campus shortly after noon Wednesday to head for their date with the top-seeded Kansas Jayhawks (33-3) on Friday night.
A berth in the elite eight is on the line.
Villanova is coming off a resounding win over Siena.
This is the third time in four years that coach Jay Wright has guided Villanova to the sweet 16.
Nova pounded Kansas back in 2005, when the Jayhawks were ranked number two. Wildcats fans are hoping for a repeat performance.
