A spokesman for the state Department of Justice says Biden was in the office on Wednesday meeting with staff.
The 44-year-old Biden was admitted last month to the University of Texas MD Anderson Cancer Center after becoming weak and disoriented during a vacation in Indiana.
His hospitalization came two weeks after emergency dispatchers received a call from Vice President Joe Biden's Delaware home, where Beau Biden has been staying, regarding a report of a possible stroke. Biden suffered a minor stroke in 2010.
Biden's family has said he underwent "a successful procedure" in Houston, but they have not provided any details.